Scientist - Chemistry

Responsibilities of this position will include:

• The design and synthesis of bioconjugates of oligonucleotides and small organic molecules.
• Purification and analysis of nucleic acid bioconjugates using modern analytical techniques (primarily semi-preparative HPLC, dPAGE, and LC-MS).
• Prepare DNA-tagged chemical libraries using the company's DNA Programmed Chemistry (DPC) platform.
• Conduct multi-step synthesis of novel building blocks and linkers as precursors for the preparation of oligo-conjugates and DNA-tagged chemical libraries.
• Develop methodology and optimize reaction conditions for the exploration of novel reaction in the context of DNA programmed chemistry.
• Accurately record experimental work and present results to both internal and external audiences.

Education/Experience

• A Ph.D. in organic or bioorganic chemistry with relevant postdoctoral experience. An exceptional MS scientist with at least 5 years of relevant research experience will also be considered.
• Experience with bioconjugate chemistry is highly desirable.
• A record of peer reviewed publications and presentations.
• Excellent verbal and written communication skills and the ability to work in a multi-discipline team environment.

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