RFA1 rabbit pAb - 50 μL

Function: It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the replication factor A protein 1 family. subunit: Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.