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CD45 / LCA (Leucocyte Marker)(Bra55) , CF640R conjugate , 0.1mg / mL

https://www.ensemblediscovery.com/web/image/product.template/171939/image_1920?unique=4f1ed46
CD45R , also designated CD45 and PTPRC , has been identified as a transmembrane glycoprotein , broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4 , 5 , and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4) , CD45RB (exon 5) , CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R , while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.

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Garantie satisfait ou remboursé de 30 jours
Expédition : 2-3 jours ouvrables