ARIH2 Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : HT005 antibody; all trans retinoic acid inducible RING finger antibody; Ari 2 antibody; Ari-2 antibody; ARI2 antibody; ARI2_HUMAN antibody; Ariadne 2 antibody; Ariadne 2 protein homolog antibody; ariadne homolog 2 (Drosophila) antibody; ariadne homolog 2 antibody; Ariadne RBR E3 ubiquitin protein ligase 2 antibody; ARIH 2 antibody; Arih2 antibody; E3 ubiquitin protein ligase ARIH2 antibody; E3 ubiquitin-protein ligase ARIH2 antibody; protein ariadne 2 homolog antibody; Protein ariadne-2 homolog antibody; Triad 1 antibody; TRIAD1 antibody; Triad1 protein antibody; UIP48 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95376
Immunogen : Recombinant Human E3 ubiquitin-protein ligase ARIH2 protein (43-360AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conj µgating enzyme E2 UBE2L3 (PubMed : 16118314, PubMed : 17646546, PubMed : 19340006, PubMed : 24076655). Acts as an atypical E3 ubiquitin-protein ligase by working together with c µLlin-5-RING ubiquitin ligase complex (ECS complex, also named CRL5 complex) and initiating ubiquitination of ECS substrates : associates with ECS complex and specifically mediates addition of the first ubiquitin on ECS targets (By similarity). The initial ubiquitin is then elongated (By similarity). E3 ubiquitin-protein ligase activity is activated upon binding to neddylated form of the ECS complex (PubMed : 24076655). Mediates \\\'Lys-6\\\', \\\'Lys-48\\\'-and \\\'Lys-63\\\'-linked polyubiquitination (PubMed : 16118314, PubMed : 17646546, PubMed : 19340006). May play a role in myelopoiesis (PubMed : 19340006).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ARIH2
Research Areas : Epigenetics and Nuclear Signaling; Cell biology