ASIP Antibody HRP conjugated

Volume : 50 µg
Clone Number :
Aliases : ASIP antibody; AGTI antibody; AGTIL antibody; ASP antibody; Agouti-signaling protein antibody; ASP antibody; Agouti switch protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P42127
Immunogen : Recombinant Human Agouti-signaling protein (23-112AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in the reg µLation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-reg µLation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Co µLd well play a role in neuroendocrine aspects of melanocortin action. May have some functional role in reg µLating the lipid metabolism with adipocytes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ASIP
Research Areas : Neuroscience; Signal transduction