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ATXN3 Antibody Biotin conjugated

https://www.proteomika.com/web/image/product.template/52142/image_1920?unique=2e10e05

Volume : 50 µg
Clone Number :
Aliases : AT3 antibody; Ataxin 3 antibody; ataxin 3 variant h antibody; ataxin 3 variant m antibody; ataxin 3 variant ref antibody; Ataxin-3 antibody; ATX3 antibody; ATX3_HUMAN antibody; ATXN3 antibody; EC 3.4.22. antibody; JOS antibody; Josephin antibody; Machado Joseph disease (spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, autosomal dominant, ataxin 3) antibody; Machado Joseph disease antibody; Machado Joseph disease protein 1 antibody; Machado-Joseph disease protein 1 antibody; Machado-Joseph disease protein 1 homolog antibody; MJD antibody; MJD gene antibody; MJD1 antibody; Olivopontocerebellar ataxia 3 antibody; OTTHUMP00000221583 antibody; OTTHUMP00000221585 antibody; OTTHUMP00000221586 antibody; OTTHUMP00000221587 antibody; OTTHUMP00000231995 antibody; OTTHUMP00000231997 antibody; Rsca3 antibody; SCA3 antibody; SCA3 gene antibody; Spinocerebellar ataxia type 3 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P54252
Immunogen : Recombinant Human Ataxin-3 protein (1-288AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton reg µLation, myogenesis and degradation of misfolded chaperone substrates. Binds long polyubiquitin chains and trims them, while it has weak or no activity against chains of 4 or less ubiquitins. Involved in degradation of misfolded chaperone substrates via its interaction with STUB1/CHIP : recruited to monoubiquitinated STUB1/CHIP, and restricts the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. In response to misfolded substrate ubiquitination, mediates deubiquitination of monoubiquitinated STUB1/CHIP. Interacts with key reg µLators of transcription and represses transcription : acts as a histone-binding protein that reg µLates transcription.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN3
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience

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2.848,56 €

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Garantie satisfait ou remboursé de 30 jours
Expédition : 2-3 jours ouvrables