AURKC Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : AURKC antibody; AIE 2 antibody; Aie1 antibody; AIE2 antibody; AIK 3 antibody; AIK3 antibody; ARK 3 antibody; ARK-3 antibody; ARK3 antibody; Aur C antibody; AurC antibody; Aurkc antibody; AURKC_HUMAN antibody; aurora 3 antibody; Aurora C antibody; Aurora kinase C antibody; aurora related kinase 3 antibody; Aurora-related kinase 3 antibody; Aurora/Ipl1 related kinase 3 antibody; Aurora/Ipl1-related kinase 3 antibody; Aurora/Ipl1/Eg2 protein 2 antibody; EC 2.7.11.1 antibody; Serine threonine protein kinase 13 antibody; serine/threonine kinase 13 (aurora/IPL1 like) antibody; serine/threonine protein kinase aurora C antibody; Serine/threonine-protein kinase 13 antibody; Serine/threonine-protein kinase aurora-C antibody; SPGF5 antibody; STK13 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UQB9
Immunogen : Recombinant Human Aurora kinase C protein (12-143AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key reg µLator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtub µLe stabilization and spindle assembly. Plays also a role in meiosis and more partic µLarly in spermatogenesis. Has redundant cell µLar functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at \'Ser-10\' and \'Ser-28\'. AURKC phosphorylates the CPC complex subunits BIRC5/survivin and INCENP leading to increased AURKC activity. Phosphorylates TACC1 another protein involved in cell division, at \'Ser-228\'.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AURKC
Research Areas : Cell biology