ARHGEF18 Antibody HRP conjugated

Volume : 50 µg
Clone Number :
Aliases : 114 kDa Rho specific guanine nucleotide exchange factor antibody; 114 kDa Rho-specific guanine nucleotide exchange factor antibody; ARHGEF 18 antibody; Arhgef18 antibody; ARHGI_HUMAN antibody; KIAA0521 antibody; MGC15913 antibody; p114 Rho GEF antibody; p114-Rho-GEF antibody; p114RhoGEF antibody; Rho guanine nucleotide exchange factor 18 antibody; Rho specific guanine nucleotide exchange factor p114 antibody; Rho/Rac guanine nucleotide exchange factor (GEF) 18 antibody; Rho/Rac guanine nucleotide exchange factor 18 antibody; SA RhoGEF antibody; SA-RhoGEF antibody; Septin associated RhoGEF antibody; Septin-associated RhoGEF antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6ZSZ5
Immunogen : Recombinant Human Rho guanine nucleotide exchange factor 18 protein (159-551AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases. Its activation induces formation of actin stress fibers. Also act as a GEF for RAC1 inducing production of reactive oxygen species (ROS). Does not act as a GEF for CDC42. The G protein beta-gamma (Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production. Required for EPB41L4B-mediated reg µLation of the circumferential actomyosin belt in epithelial cells (PubMed : 22006950).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ARHGEF18
Research Areas : Signal transduction