ATAT1 Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : Acetyltransferase mec 17 homolog antibody; Acetyltransferase mec-17 homolog antibody; Alpha TAT antibody; Alpha tub µLin acetyltransferase 1 antibody; Alpha tub µLin N acetyltransferase antibody; Alpha-TAT antibody; Alpha-tub µLin N-acetyltransferase antibody; ATAT_HUMAN antibody; ATAT1 antibody; Chromosome 6 open reading frame 134 antibody; Hypothetical protein LOC79969 antibody; MEC17 antibody; Nbla00487 antibody; TAT antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5SQI0
Immunogen : Recombinant Human Alpha-tub µLin N-acetyltransferase 1 protein (194-238AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Specifically acetylates \'Lys-40\' in alpha-tub µLin on the lumenal side of microtub µLes. Promotes microtub µLe destabilization and accelerates microtub µLe dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tub µLin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtub µLe thro µgh each end and diffuses quickly thro µghout the lumen of microtub µLes. Acetylates only long/old microtub µLes because of its slow acetylation rate since it does not have time to act on dynamically unstable microtub µLes before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, thro µgh AP2A2-dependent acetylation of alpha-tub µLin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATAT1
Research Areas : Cell biology