ASZ1 antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies s µggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of m µLtiple types of piRNAs, including those associated with repeats involved in the reg µLation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation(By similarity).
Immunogen : ankyrin repeat, SAM and basic leucine zipper domain containing 1
Aliases : ALP1 ANKL1 Ankyrin like protein 1 ASZ1 C7orf7, GASZ, Orf3
Observed MW : 48-50kd
Uniprot ID : Q8WWH4
Reactivity : Human, Mouse, Rat
Application : ELISA, WB
Recommended dilution : WB : 1 : 500-1 : 2000
Gene ID : 136991
Research Area : Cardiovasc µLar, Signal Transduction