ABCC6 antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : The ATP-binding cassette transporter 6 (ABCC6) gene, also named as MRP6, is a cell µLar transmembrane protein transporter and belongs to ATP-binding cassette (ABC) family. ABCC6 is an ATP-dependent transporter contains two ATP-binding domains. It is mainly found in the liver, the proximal tub µLes of the kidneys and the intestines. ABCC6 is involved in a pathway of extracell µLar nucleotide metabolism and the reg µLation of tissue calcification. Mutations of ABCC6 leads to pseudoxanthoma elasticum (PXE) which is a rare autosomal recessive disorder. Mutations of ABCC6 can also lead generalized arterial calcification of infancy-2 (GACI2).
Immunogen : ATP-binding cassette, sub-family C (CFTR/MRP), member 6
Aliases : ABC34, ABCC6, ARA, EST349056, MLP1 MOAT E, MOATE, MRP6, PXE, PXE1
Observed MW : 165 kDa
Uniprot ID : O95255
Reactivity : Human
Application : ELISA, IHC
Recommended dilution : IHC : 1 : 20-1 : 200
Gene ID :
Research Area :