PLS1 rabbit pAb - 100 μL

Cofactor: Calcium. function: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. function: May play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes. May contribute to cytokine-regulated cell proliferation and differentiation. induction: By phosphorylation by PKC. Induced by INFB1 in response to a viral infection. online information: Scramblase entry, PTM: Known to be palmitoylated at one, yet undefined, site. similarity: Belongs to the phospholipid scramblase family. subunit: Interacts with ABL. tissue specificity: Expressed in platelets, erythrocyte membranes, lymphocytes, spleen, thymus, prostate, testis, uterus, intestine, colon, heart, placenta, lung, liver, kidney and pancreas. Not detected in brain and skeletal muscle.