Se rendre au contenu

RIPK1 rabbit pAb - 100 μL

https://www.ensemblediscovery.com/web/image/product.template/636566/image_1920?unique=a2b8353
Catalytic activity: ATP + a protein = ADP + a phosphoprotein. function: Promotes apoptosis and activation of NF-kappa-B. Required for TNFRSF1A mediated activation of NF-kappa-B. PTM: Autophosphorylated on serine and threonine residues. PTM: Proteolytically cleaved by caspase-8 during TNF-induced apoptosis. Cleavage abolishes NF-kappa-B activation and enhances pro-apototic signaling through the TRADD-FADD interaction. similarity: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. similarity: Contains 1 death domain. similarity: Contains 1 protein kinase domain. subunit: Binds to the death domain of TNFRSF6 and TRADD. Is recruited by TRADD to TNFRSF1A in a TNF-dependent process. Binds RIPK3, UBCE7IP1 isoform 3 (ZIN), EGFR, IKBKG, TRAF1, TRAF2 and TRAF3. Interacts with BNLF1. Interacts with SQSTM1 upon TNF-alpha stimulation. May interacts with MAVS/IPS1.

348,00 348.0 USD 348,00

348,00

Not Available For Sale

(0,00 / Unité(s))

Cette combinaison n'existe pas.

Conditions générales
Garantie satisfait ou remboursé de 30 jours
Expédition : 2-3 jours ouvrables

Distributed by Gentaur

RIPK1 rabbit pAb
View the Technical Datasheet of the product below